Once you begin obtaining high-tier rewards, the Horadric Fortress becomes an excellent source of potions and vials. The enemies and bosses inside scale with your power, increasing the drop rate and overall value of Diablo IV gold each run.

Chests and Seasonal Stashes
Horadric Vials can also appear randomly in world chests, seasonal caches, and stashes earned through event progression. These rewards scale with your level and world tier, so engaging with seasonal mechanics and using the Whispering Tree to speed up your level progression is recommended.

Horadric Knowledge and Focus
Fighting in Helltides, completing Nightmare Dungeons, and clearing Horadric Vaults grants Horadric Knowledge, which passively builds up as Diablo 4 gold you play. As your knowledge increases, you gain access to Horadric Focus, which lets you claim stashes packed with high-tier loot, including multiple Horadric Vials.