Tadalista 20 mg (tadalafil) can cause muscle pain, but this side effect is relatively uncommon. Here's when and why muscle pain might occur: When Can Tadalista 20 mg Cause Muscle Pain? After Starting the Medication: Muscle pain, especially back pain or muscle aches, can appear within 12 to 24 hours after taking tadalafil and typically resolves within 48 hours. Higher Dosage or Sensitivity: At the 20 mg dose, which is the higher end for tadalafil treatment, muscle pain is more likely than at lower doses. Some people may be more sensitive to the medication. Due to Vasodilation and Muscle Relaxation: Tadalafil works by Tadalista 20 mg smooth muscles and increasing blood flow, which can sometimes cause muscle aches or pain as a side effect. Prolonged Use or Repeated Doses: Continuous or frequent use might increase the chance of muscle-related side effects in some people. Typical Characteristics of Muscle Pain with Tadalafil: Usually mild to moderate in intensity Commonly affects the lower back, thighs, or muscles around the pelvis Often transient and resolves without treatment What to Do If You Experience Muscle Pain? Rest and hydration often help ease the discomfort. Over-the-counter pain relievers (like acetaminophen or ibuprofen) may be used, but consult your doctor first. If muscle pain is severe, persistent, or accompanied by other symptoms (like weakness or swelling), seek medical advice promptly.